pStab

Prediction of Stable Mutants, Unfolding Curves, Stability Maps and Protein Electrostatic Frustration

General Instructions

  • The protein length should be between 30 – 300 amino acids for calculating the effect of mutations on the net charge-charge interaction energy (Visit help page for more details).
  • The protein length should be ≤ 150 amino acids for predicting folding thermodynamics from the WSME model (To know about the model in detail, visit help page).
  • The uploaded PDB file
    • Should not contain any hetero atom(s) or non-standard amino acid(s).
    • Should not contain any disulfide bonds.
    • Should contain the complete description of heavy atoms (To model missing atoms, visit here).

 Predict only the unfolding curve and local stability profile of the input protein (Thermodynamics module).

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  Protein Biophysics Lab

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2017, Maintained by Protein Biophysics Lab, IIT Madras, Chennai-36, India

Last Updated: September 13, 2017